Immunogenecity of Modified Alkane Polymers Is Mediated through TLR1/2 Activation

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Immunogenecity of Modified Alkane Polymers Is Mediated through TLR1/2 Activation

BACKGROUND With the advancement of biomedical technology, artificial materials have been developed to replace diseased, damaged or nonfunctional body parts. Among such materials, ultra high molecular weight alkane or modified alkyl polymers have been extensively used in heart valves, stents, pacemakers, ear implants, as well as total joint replacement devices. Although much research has been un...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2008

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0002438